Brock Purdy has an opportunity to etch his name in the NFL record books when the 49ers face the Los Angeles Rams on Sunday at SoFi Stadium.

The San Francisco 49ers’ starting tight end Sunday against the Rams will be a 2017 fifth-round pick who played collegiately ...

San Francisco is already without All-Pro running back Christian McCaffrey, who went on injured reserve last week with ...

Brock Purdy is familiar with the feeling of victory at SoFi Stadium, having helped the San Francisco 49ers to a Week 2 win ...

Against the Rams, San Francisco will be without Kittle, running back Christian McCaffrey and receiver Deebo Samuel. McCaffrey ...

When NFL drafts come around, tailbacks are shunned as if the football they’re carrying is Limburger with a skin made of ...

SANTA CLARA, Calif. (AP) — All-Pro tight end George Kittle will miss the San Francisco 49ers' game on Sunday against the Los ...

San Francisco 49ers safety Talanoa Hufanga is poised to make his season debut on Sunday against the Los Angeles Rams.

The San Francisco 49ers will be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams.

Here are the latest predictions, picks, and odds for the 2024 NFL Week 3 matchup between the San Francisco 49ers vs. Los ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

There may not be two teams more injured than the Los Angeles Rams and San Francisco 49ers, which will have a big impact on ...